Rosa damascena
Rosa damascena mill L, commonly known as Damask rose, is known as Gole Mohammadi in Iran. It is one of the most important species of Rosaceae family. Rosaceae are well- known ornamental plants and have been referred to as the king of flowers. At present time, over 200 rose species and more than 18000 cultivars form of the plant have been identified. Apart from the use of R. damascena as ornamental plants in parks, gardens, and houses, they are principally cultivated for using in perfume, medicine and food industry.
This plant contains several components such as terpenes, glycosides, flavonoids, and anthocyanins that have beneficial effects on human health. The pharmacological effects of R. damascene are widespread. Most of the CNS effects are hypnotic, analgesic, and anticonvulsant effects. The respiratory, cardiovascular, laxative, antidiabetic, antimicrobial, anti-HIV, anti-inflammatory, and antioxidant are other effects of this plant. The medicinal functions of Rosaceae are partly attributed to their abundance of phenolics compound. Phenolics possess a wide range of pharmacological activities, such as antioxidants, free-radical scavengers, anticancer, anti-inflammatory, antimutagenic, and antidepressant.

History
There are evidences that Rosaceae family is an ancient plant. Some fossils of rose are found in America that are 30 million years old. The origin of Damask rose is the Middle East and some evidences indicate that the origin of rose water is Iran, but the origin of its fragrant essential oil and extracts is Greece. This plant is cultivated in all over the world including Iran, Europe, Bulgaria, Turkey and India. The major cultivation areas of R. damascena in Iran are Kashan, Fars and Azerbaijan, among them Kashan is the most famous on.It is believed that the crude distillation of roses for the oil was originated from in the late 7th century AD, and spread to the provinces of later in 14th century. Iran was the main producer of rose essential oil until the 16th century and exported it to all around the world.
Traditional uses
The most therapeutic effects of R. damascena in ancient medicine are including treatment of abdominal and chest pain, strengthening the heart, treatment of menstrual bleeding and digestive problems, and reduction of inflammation, especially of the neck. North American Indian tribes used a decoction of the root of R. damascena plant as a cough remedy to ease children’s cough. This plant is also used as a gentle laxative. Rose essential oil heals depression, grief, nervous stress and tension. It helps in the reduction of thirst, healing old cough, wound healing, and skin health. Vapor therapy of rose essential oil is helpful for some allergies, headaches, and migraine.